Introduction to Genome theme

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The visualization of genomes can be achieved through the tools presented in this section, ranging from techniques that allow genome browsing to the exploration of new sequences either generated from public resources or within the laboratory. The study of genomes is often based on available reference genome sequences of specific species and the characteristics of that genome are now largely digitalised through sequencing technology. The types of assays are only limited by the researchers imaginations, but include the location and quantification of alternate transcripts of genes, the differential use of transcription start sites, transcription factor binding factors, epigenetic mofication of histones and genomic DNA, as well genetic variation data, just name a few. Automated tools allow the researchers to analyse, manipulate and integrate large-scale data sets, providing a powerful complement to human interpretation.