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CGAP

The Contact Geometry Analysis Plugin (CGAP) (for CMView) allows incorporation of geometric orientation propensities into the process of interactive protein modeling and can be used for the generation of improved energy functions. It further supports the analysis of model quality, as it directly illustrates model consistency with known spatial propensities which, in turn, enables users to detect possible structural errors.

CGAP was developed as Plugin for CMView.

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Project development

Institution: University of Stuttgart, University of Magdeburg, Max Planck Institute for Molecular Genetics, Berlin

Future applications of the introduced visualizations include flexible docking and structure-based drug design as well as the development into an interactive modeling environment.

Matse

Microarray Time-series Explorer (MATSE) is a high quality interactive visualisation software application for the analysis of microarray time-course data.

  • Links to R and the inclusion of clustering visualisations
  • Multi-sample experiments linked in multiple views
  • Visualisations that accommodate missing/null values in the data
  • Storage and retrieval of selections, making it easier for biologists to share findings
  • Visualisation of predefined gene groupings
  • Import/export of gene groupings
  • Sliders supporting common data queries (e.g. maximum fold change for a gene)
 
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Project development

Institution: IIDI

This tool was developed at the Institute for Informatics and Digital Innovation using a Scottish Enterprise grant (project reference number L/JR/POC/8-OET003). The intial concept for this time-series explorer was first investigated during the PhD work of P Craig. The concept was later expanded, improved and re-developed with a Scottish Enterprise grant, and partipation from active industrial partner firm and a number of academic bio-informaticians. 

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