Using Tablet for visual exploration of second-generation sequencing data

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TitleUsing Tablet for visual exploration of second-generation sequencing data
Publication TypeJournal Article
Year of Publication2013
AuthorsMilne, I, Stephen, G, Bayer, M, Cock, PJA, Pritchard, L, Cardle, L, Shaw, PD, Marshall, D
JournalBriefings in Bioinformatics
Pagination193 - 202
Date PublishedJan-03-2013

The advent of second-generation sequencing (2GS) has provided a range of significant new challenges for the visualization of sequence assemblies. These include the large volume of data being generated, short-read lengths and different data types and data formats associated with the diversity of new sequencing technologies. This article illustrates how Tablet—a high-performance graphical viewer for visualization of 2GS assemblies and read mappings—plays an important role in the analysis of these data. We present Tablet, and through a selection of use cases, demonstrate its value in quality assurance and scientific discovery, through features such as whole-reference coverage overviews, variant highlighting, paired-end read mark-up, GFF3-based feature tracks and protein translations. We discuss the computing and visualization techniques utilized to provide a rich and responsive graphical environment that enables users to view a range of file formats with ease. Tablet installers can be freely downloaded from in 32 or 64-bit versions for Windows, OS X, Linux or Solaris. For further details on the Tablet, contact

Short TitleBriefings in Bioinformatics
Refereed DesignationUnknown