CAB Visualization

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Visualization of Cytoskeletal Structures in Fibrillar Scaffolds from 3-Dimensional Confocal Image

These visual-analytic tools delineate specific structures involving F-actin in cells. Concave actin bundles (CABs) often occur in hybrid cell-seeded fibrillar scaffolds and seem to envelope the fibers, as a possible mechanism of stable attachment. There is much uncertainty that accompanies the detection and the identification of fibers. These tools rely on well-known algorithms of image analysis.

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Institution: The Ohio State University

This work was supported in part by the NIH Grants RC2 AG-036559 and R01 HL-096524 (to NM).